OR2AT4 Olfactory Receptor
| Gene Symbol | OR2AT41 (View this gene in GeneCards) |
| Family | 2 |
| Subfamily | AT |
| Pseudogene | No |
| CORP pseudogene probability score | 0.1 (functional) |
| Aliases | OR11-265, HsOR11.16.2 |
| External Ids | HGNC: 19620 GeneBank: BK004820, NM_001005285 |
| Build #39 labels | OR2AT4 |
| Chromosomal location | 11:75,088,754-75,089,713 (-) |
| Cluster | 11@75 |
| Synteny | CLIC#28 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR2AT1P | 83.4% | 253 |
| OR2AT2P | 82.52% | 309 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR2AT2B | 92% | 309 |
| Mouse | Or2at4 | 88% | 310 |
| Rat | Or2at1 | 84% | 315 |
| Cow | OR2AT2B | 90% | 309 |
| Orang | OR2AT2P | 81% | 315 |
| Horse | OR2AT2D | 86% | 322 |
| Horse | OR2AT2EP | 83% | 320 |
| Horse | OR2AT2 | 85% | 309 |
| Chimp | OR2AT2P | 81% | 320 |
Expression evidences
| Source | Accession |
|---|---|
| mRNA | BC136959 |
| GNF Atlas2 | gnf1h02275_at |
Sequence information
| Nucleotide sequence |
ATGGATGCCACAGCCTGTAATGAATCAGTGGATGGCTCACCCGTCTTCTATCTATTGGGC ATCCCCTCTCTGCCAGAGACCTTCTTCCTCCCTGTGTTTTTTATTTTCCTCCTCTTCTAC CTTCTCATCCTGATGGGTAATGCCCTGATCCTGGTGGCCGTGGTGGCAGAGCCCAGCCTC CACAAGCCCATGTACTTCTTTCTGATCAATCTCTCCACCTTGGACATCCTTTTCACCACA ACCACTGTCCCCAAGATGCTGTCCTTATTCTTGCTTGGGGACCGCTTCCTCAGCTTTTCT TCCTGCTTACTGCAGATGTACCTCTTCCAAAGTTTTACATGTTCAGAAGCCTTCATCCTG GTGGTCATGGCCTATGACCGCTATGTGGCTATCTGCCACCCACTGCACTACCCTGTCCTC ATGAACCCACAGACCAATGCTACCTTGGCAGCCAGTGCCTGGCTAACTGCCCTCCTCCTG CCCATCCCAGCAGTAGTAAGGACCTCCCAGATGGCATATAACAGCATTGCCTACATCTAC CACTGCTTCTGTGATCATCTGGCTGTGGTCCAGGCCTCCTGCTCTGACACCACCCCCCAG ACCCTCATGGGCTTCTGCATCGCCATGGTGGTGTCCTTCCTCCCCCTTCTCCTGGTGCTT CTCTCCTATGTCCACATCCTGGCCTCAGTGCTTCGCATCAGTTCCCTAGAAGGACGGGCA AAAGCCTTCTCCACCTGCAGCTCCCACCTTCTGGTCGTGGGCACCTACTACTCATCTATT GCCATAGCCTACGTGGCCTACAGGGCTGACCTGCCCCTTGACTTCCATATCATGGGCAAT GTGGTATATGCCATTCTCACACCAATTCTCAACCCCCTCATTTACACGCTGAGAAACAGG GATGTAAAGGCAGCCATCACCAAAATCATGTCTCAAGACCCAGGCTGTGACAGGAGCATT |
| Conceptual translation |
MDATACNESVDGSPVFYLLGIPSLPETFFLPVFFIFLLFYLLILMGNALILVAVVAEPSL HKPMYFFLINLSTLDILFTTTTVPKMLSLFLLGDRFLSFSSCLLQMYLFQSFTCSEAFIL VVMAYDRYVAICHPLHYPVLMNPQTNATLAASAWLTALLLPIPAVVRTSQMAYNSIAYIY HCFCDHLAVVQASCSDTTPQTLMGFCIAMVVSFLPLLLVLLSYVHILASVLRISSLEGRA KAFSTCSSHLLVVGTYYSSIAIAYVAYRADLPLDFHIMGNVVYAILTPILNPLIYTLRNR DVKAAITKIMSQDPGCDRSI Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 11 | 74,800,027 | 74,800,027 | SYN | A/G | S/S | rs61897539 (DbSNP) |
| 11 | 74,800,600 | 74,800,600 | SYN | A/G | A/A | rs11236324 (DbSNP) |
| 11 | 75,089,093 | 75,089,093 | SYN | G/A | I/I | 1000GP (CEU) |
| 11 | 100 | -100 | NS | G/C | A/G | 1000GP (YRI) |
| 11 | 100 | -100 | SYN | T/C | S/S | 1000GP (YRI, YRI) |
Variations - CNVs
| Chr | Start | End | Type | Sources |
|---|---|---|---|---|
| CopyNumber | 212 (Hasin) | |||
| 11 | 74,797,799 | 74,800,858 | Deletion | #227 (Waszak) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| A242G | V15I | % Freq | CORP | |
|---|---|---|---|---|
| 1 | A | V | 98.14 | 0.184 |
| 2 | G | V | 1.20 | 0.392 |
| 3 | A | I | 0.66 | 0.184 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR2AT4.aApr07-unspliced | main_exon | 3UTR | chr11 | 75,088,751 | 75,088,754 | - |
| CDS | chr11 | 75,088,754 | 75,089,713 | - | ||