OR2B11 Olfactory Receptor
| Gene Symbol | OR2B111 (View this gene in GeneCards) |
| Family | 2 |
| Subfamily | B |
| Pseudogene | No |
| CORP pseudogene probability score | 0.28 (functional) |
| Aliases | HsOR1.5.1 |
| External Ids | HGNC: 31249 GeneBank: NM_001004492 |
| Build #39 labels | |
| Chromosomal location | 1:247,451,032-247,451,982 (-) |
| Cluster | 1@248 |
| Synteny | CLIC#5 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR2B2 | 58.53% | 299 |
| OR2B3 | 59.27% | 302 |
| OR2B4P | 61.36% | 308 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR2B2 | 63% | 301 |
| Mouse | Or2b11 | 87% | 317 |
| Rat | Or2b11 | 84% | 317 |
| Cow | OR2B2 | 63% | 300 |
| Orang | OR2B4P | 62% | 311 |
| Horse | OR2B2 | 63% | 303 |
| Chimp | OR2B3 | 59% | 303 |
Expression evidences
| Source | Accession |
|---|---|
| ESTs | BF838729 |
| mRNA | BC137205 |
| GNF Atlas2 | gnf1h09716_at |
Sequence information
| Nucleotide sequence |
ATGAAAAGTGACAACCATAGCTTCTTAGGGGACTCCCCTAAAGCCTTCATCCTTCTGGGT GTGTCTGACAGGCCGTGGCTGGAACTCCCTCTCTTTGTGGTCCTCCTGCTGTCCTATGTG CTGGCCATGTTGGGGAACGTCGCCATCATCCTGGCATCCCGGGTGGATCCTCAACTCCAC AGCCCCATGTACATCTTCCTCAGTCACCTGTCCTTCCTGGACCTCTGCTACACCACCACG ACAGTCCCTCAGATGCTGGTCAACATGGGCAGTTCCCAGAAGACCATCAGCTATGGAGGC TGCACTGTGCAATATGCAGTCTTCCACTGGCTGGGATGCACGGAGTGCATCGTCCTGGCC GCCATGGCCCTGGACCGCTACGTGGCCATCTGCAAGCCCCTGCACTATGCCGTTCTCATG CACCGTGCTCTCTGTCAGCAGCTCGTGGCTCTGGCCTGGCTCAGTGGCTTCGGCAACTCC TTCGTGCAGGTGGTCCTGACGGTGCAATTGCCATTCTGCGGGCGGCAGGTGCTGAACAAC TTTTTCTGTGAGGTGCCGGCCGTGATCAAGCTGTCGTGTGCTGACACCGCTGTGAATGAC ACCATACTGGCTGTGCTGGTGGCCTTCTTCGTGTTGGTGCCCCTGGCTCTCATCCTTCTC TCCTATGGCTTTATTGCCCGGGCAGTGCTCAGGATCCAGTCCTCCAAGGGACGACACAAG GCCTTTGGGACGTGTTCCTCCCACCTGATGATCGTCTCCCTCTTCTACCTACCTGCGATT TACATGTATCTGCAGCCCCCTTCCAGCTACTCCCAAGAGCAGGGCAAATTTATTTCTCTC TTCTATTCCATAATCACCCCCACTCTCAATCCCTTCACCTACACCCTGAGAAATAAAGAT ATGAAGGGGGCTCTGAGGAGACTTCTGGCCAGGATCTGGAGGCTCTGTGGA |
| Conceptual translation |
MKSDNHSFLGDSPKAFILLGVSDRPWLELPLFVVLLLSYVLAMLGNVAIILASRVDPQLH SPMYIFLSHLSFLDLCYTTTTVPQMLVNMGSSQKTISYGGCTVQYAVFHWLGCTECIVLA AMALDRYVAICKPLHYAVLMHRALCQQLVALAWLSGFGNSFVQVVLTVQLPFCGRQVLNN FFCEVPAVIKLSCADTAVNDTILAVLVAFFVLVPLALILLSYGFIARAVLRIQSSKGRHK AFGTCSSHLMIVSLFYLPAIYMYLQPPSSYSQEQGKFISLFYSIITPTLNPFTYTLRNKD MKGALRRLLARIWRLCG Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 1 | 100 | -100 | NS | T/C | D/G | 1000GP (YRI, YRI, YRI, YRI, YRI, YRI, YRI, YRI, YRI) |
| 1 | 100 | -100 | SYN | C/T | T/T | 1000GP (YRI, YRI, YRI, YRI) |
| 1 | 247,451,084 | 247,451,084 | NS | T/C | D/G | 1000GP (CEU) |
| 1 | 247,451,105 | 247,451,105 | NS | G/A | T/I | 1000GP (CEU) |
| 1 | 247,451,251 | 247,451,251 | SYN | C/T | T/T | 1000GP (CEU) |
| 1 | 247,451,315 | 247,451,315 | NS | C/T | G/D | 1000GP (CEU, CHBJPT) |
| 1 | 247,451,367 | 247,451,367 | NS | G/C | L/V | 1000GP (CHBJPT) |
| 1 | 247,451,369 | 247,451,369 | NS | A/C | V/G | 1000GP (CHBJPT) |
| 1 | 247,451,391 | 247,451,391 | NS | C/T | V/M | 1000GP (CEU, CHBJPT) |
| 1 | 247,451,448 | 247,451,448 | NS | T/C | N/D | 1000GP (CHBJPT) |
| 1 | 247,451,594 | 247,451,594 | NS | A/C | I/S | 1000GP (CEU, CHBJPT) |
| 1 | 247,451,950 | 247,451,950 | SYN | G/A | D/D | 1000GP (CEU, CHBJPT) |
| 1 | 247,614,386 | 247,614,386 | NS | C/T | G/D | rs12070953 (DbSNP) |
| 1 | 247,614,407 | 247,614,407 | NS | A/G | I/T | rs12065526 (DbSNP) |
| 1 | 247,614,553 | 247,614,553 | SYN | C/T | T/T | rs12086048 (DbSNP) |
| 1 | 247,614,617 | 247,614,617 | NS | C/T | G/D | rs4925663 (DbSNP) |
| 1 | 247,614,657 | 247,614,657 | NS | A/G | F/L | rs73140586 (DbSNP) |
| 1 | 247,614,693 | 247,614,693 | NS | C/T | V/M | rs6695302 (DbSNP) |
| 1 | 247,614,763 | 247,614,763 | SYN | C/T | G/G | rs58058243 (DbSNP) |
| 1 | 247,614,784 | 247,614,784 | SYN | C/G | T/T | rs74154654 (DbSNP) |
| 1 | 247,614,896 | 247,614,896 | NS | A/C | I/S | rs11583410 (DbSNP) |
| 1 | 247,614,925 | 247,614,925 | SYN | A/G | A/A | rs73140588 (DbSNP) |
| 1 | 247,615,154 | 247,615,153 | Ins(1) | -/C | rs35822304 (DbSNP) | |
| 1 | 247,615,252 | 247,615,252 | SYN | A/G | D/D | rs12028142 (DbSNP) |
| 1 | 247,615,263 | 247,615,263 | Del(1) | -/A | rs35305980 (DbSNP) |
Variations - CNVs
| Chr | Start | End | Type | Sources |
|---|---|---|---|---|
| 1 | 247,074,430 | 248,328,835 | CopyNumber | Variation_6816 (DGV) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| D300G | T293I | N290H | R231M | R227W | G223D | F210L | D200E | V198M | N179D | I130S | N46S | S12Y | % Freq | CORP | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | D | T | N | R | R | D | F | D | M | N | I | N | S | 32.26 | 0.209 |
| 2 | D | T | N | R | R | G | F | D | M | N | S | N | S | 29.26 | 0.720 |
| 3 | D | T | N | R | R | G | F | D | M | N | I | N | S | 13.90 | 0.209 |
| 4 | G | I | N | R | R | G | F | D | M | N | I | N | S | 7.60 | 0.209 |
| 5 | D | T | N | R | R | D | F | D | M | N | S | N | S | 4.99 | 0.720 |
| 6 | D | T | N | R | R | G | L | D | V | N | I | N | S | 4.15 | 0.209 |
| 7 | G | I | N | R | R | G | L | D | V | N | I | N | S | 1.46 | 0.209 |
| 8 | G | I | N | R | W | G | L | D | V | N | I | N | S | 0.77 | 0.209 |
| 9 | G | I | N | R | R | G | F | D | V | N | I | N | S | 0.61 | 0.209 |
| 10 | D | T | N | R | R | G | L | D | V | N | S | N | S | 0.61 | 0.720 |
| 11 | D | T | N | R | R | D | F | D | V | N | I | N | S | 0.61 | 0.209 |
| 12 | D | T | N | R | R | G | F | D | V | N | I | N | S | 0.54 | 0.209 |
| 13 | D | T | N | R | R | G | F | D | M | N | S | S | S | 0.38 | 1.000 |
| 14 | D | T | N | R | R | D | F | D | M | D | I | N | S | 0.38 | 0.209 |
| 15 | G | I | N | R | R | G | L | E | V | N | I | N | S | 0.31 | 0.209 |
| 16 | D | I | N | R | R | G | F | D | M | N | I | N | S | 0.23 | 0.209 |
| 17 | G | I | N | R | R | G | F | D | M | N | S | N | S | 0.23 | 0.720 |
| 18 | D | T | N | R | R | G | F | D | M | N | S | N | Y | 0.15 | 0.720 |
| 19 | D | T | H | R | R | D | F | D | M | N | I | N | S | 0.15 | 0.119 |
| 20 | D | T | N | R | W | G | F | D | M | N | S | N | S | 0.15 | 0.720 |
| 21 | D | T | N | R | R | G | F | D | V | N | S | N | S | 0.15 | 0.720 |
| 22 | D | T | N | R | R | D | F | D | V | N | S | N | S | 0.15 | 0.720 |
| 23 | D | T | N | R | R | G | F | D | M | N | I | S | S | 0.15 | 1.000 |
| 24 | D | T | N | R | R | G | L | D | V | N | I | S | S | 0.15 | 1.000 |
| 25 | D | T | N | R | R | D | F | D | M | D | S | N | S | 0.08 | 0.720 |
| 26 | D | I | N | R | R | D | F | D | M | N | I | N | S | 0.08 | 0.209 |
| 27 | D | T | N | R | R | G | F | D | V | N | S | S | S | 0.08 | 1.000 |
| 28 | D | I | N | R | R | G | F | D | M | N | S | N | S | 0.08 | 0.720 |
| 29 | D | T | N | R | R | G | L | D | M | N | I | N | S | 0.08 | 0.209 |
| 30 | D | T | N | R | R | G | F | D | M | N | I | N | Y | 0.08 | 0.209 |
| 31 | G | I | N | R | R | D | F | D | M | N | I | N | S | 0.08 | 0.209 |
| 32 | D | T | N | M | R | G | F | D | M | N | I | N | S | 0.08 | 0.209 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR2B11.aApr07-unspliced | main_exon | 3UTR | chr1 | 247,451,029 | 247,451,032 | - |
| CDS | chr1 | 247,451,032 | 247,451,982 | - | ||