OR5B17 Olfactory Receptor
| Gene Symbol | OR5B171 (View this gene in GeneCards) |
| Family | 5 |
| Subfamily | B |
| Pseudogene | No |
| CORP pseudogene probability score | 0.64 (pseudogene) |
| Aliases | OR11-237, HsOR11.12.17, ORL3415 |
| External Ids | HGNC: 15267 GeneBank: AB065849, BK004491, NM_001005489 ORDB: ORL3415 |
| Build #39 labels | OR5B17, OR5B20P |
| Chromosomal location | 11:58,358,128-58,359,069 (-) |
| Cluster | 11@58 |
| Synteny | CLIC#27 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR5B1P | 72.58% | 310 |
| OR5B2 | 71.1% | 308 |
| OR5B3 | 72.26% | 310 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR5B31 | 76% | 314 |
| Mouse | Or5b3 | 71% | 307 |
| Rat | Or5b95 | 71% | 310 |
| Cow | OR5B140 | 74% | 314 |
| Orang | OR5B3P | 71% | 310 |
| Horse | OR5B158 | 73% | 310 |
| Chimp | OR5B3 | 72% | 310 |
Expression evidences
| Source | Accession |
|---|---|
| GNF Atlas2 | gnf1h10677_at |
Sequence information
| Nucleotide sequence |
ATGGAGAATAATACAGAGGTGAGTGAATTCATCCTGCTTGGTCTAACCAATGCCCCAGAA CTACAGGTTCCCCTCTTTATCATGTTTACCCTCATCTACCTCATCACTCTGACTGGGAAC CTGGGGATGATCATATTAATCCTGCTGGACTCTCATCTCCACACTCCCATGTACTTTTTT CTCAGTAACCTGTCTCTTGCAGGCATTGGTTACTCCTCAGCTGTCACTCCAAAGGTTTTA ACTGGGTTGCTTATAGAAGACAAAGCCATCTCCTACAGTGCCTGTGCTGCTCAGATGTTC TTTTGTGCAGTCTTTGCCACTGTGGAAAATTACCTCTTGTCCTCAATGGCCTATGACCGC TACGCAGCAGTGTGTAACCCCCTACATTATACCACCACCATGACAACACGTGTGTGTGCT TGTCTGGCTATAGGCTGTTATGTCATTGGTTTTCTGAATGCTTCTATCCAAATTGGAGAT ACATTTCGCCTCTCTTTCTGCATGTCCAATGTGATTCATCACTTTTTCTGTGACAAACCA GCAGTCATTACTCTGACCTGCTCTGAGAAACACATTAGTGAGTTGATTCTTGTTCTTATA TCAAGTTTTAATGTCTTTTTTGCACTTCTTGTTACCTTGATTTCCTATCTGTTCATATTG ATCACCATTCTTAAGAGGCACACAGGTAAGGGATACCAGAAGCCTTTATCTACCTGTGGT TCTCACCTCATTGCCATTTTCTTATTTTATATAACTGTCATCATCATGTACATACGACCA AGTTCCAGTCATTCCATGGACACAGACAAAATTGCATCTGTGTTCTACACTATGATCATC CCCATGCTCAGTCCTATAGTCTATACCCTGAGGAACAAAGACGTGAAGAATGCATTCATG AAGGTTGTTGAGAAGGCAAAATATTCTCTAGATTCAGTCTTT |
| Conceptual translation |
MENNTEVSEFILLGLTNAPELQVPLFIMFTLIYLITLTGNLGMIILILLDSHLHTPMYFF LSNLSLAGIGYSSAVTPKVLTGLLIEDKAISYSACAAQMFFCAVFATVENYLLSSMAYDR YAAVCNPLHYTTTMTTRVCACLAIGCYVIGFLNASIQIGDTFRLSFCMSNVIHHFFCDKP AVITLTCSEKHISELILVLISSFNVFFALLVTLISYLFILITILKRHTGKGYQKPLSTCG SHLIAIFLFYITVIIMYIRPSSSHSMDTDKIASVFYTMIIPMLSPIVYTLRNKDVKNAFM KVVEKAKYSLDSVF Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 11 | 100 | -100 | NS | T/C | Y/C | 1000GP (YRI, YRI, YRI, YRI, YRI) |
| 11 | 100 | -100 | SYN | C/T | R/R | 1000GP (YRI) |
| 11 | 58,125,620 | 58,125,620 | NS | C/T | C/Y | rs4127353 (DbSNP) |
| 11 | 58,125,696 | 58,125,696 | NS | G/A | L/F | rs61748315 (DbSNP) |
| 11 | 58,125,774 | 58,125,774 | NS | A/G | Y/H | rs55810057 (DbSNP) |
| 11 | 58,125,812 | 58,125,812 | NS | G/A | T/I | rs61741322 (DbSNP) |
| 11 | 58,125,865 | 58,125,865 | NS | C/A | R/S | rs61744476 (DbSNP) |
| 11 | 58,126,305 | 58,126,305 | NS | A/T | L/I | rs4939208 (DbSNP) |
| 11 | 58,126,493 | 58,126,493 | NS | T/C | N/S | rs61741317 (DbSNP) |
| 11 | 58,358,147 | 58,358,147 | NS | T/C | Y/C | 1000GP (CEU, CHBJPT) |
| 11 | 58,358,301 | 58,358,301 | NS | A/G | Y/H | 1000GP (CEU) |
| 11 | 58,358,832 | 58,358,832 | NS | A/T | L/I | 1000GP (CEU, CHBJPT) |
| 11 | 58,359,006 | 58,359,006 | nonsense SNP | G/A | Q/* | 1000GP (CHBJPT) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| Y308C | Y257H | I244T | R226S | L80I | P24L | Q22* | N17S | % Freq | CORP | |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | C | Y | I | R | I | P | Q | N | 62.37 | 0.624 |
| 2 | Y | Y | I | R | L | P | Q | N | 28.57 | 0.624 |
| 3 | C | H | I | R | I | P | Q | N | 4.38 | 0.624 |
| 4 | C | Y | I | R | I | P | * | N | 1.08 | 1.200 |
| 5 | C | Y | T | R | L | P | Q | N | 1.00 | 0.624 |
| 6 | C | Y | I | R | I | P | Q | S | 1.00 | 0.624 |
| 7 | C | Y | I | S | I | P | Q | N | 0.84 | 0.624 |
| 8 | C | Y | I | R | I | L | Q | N | 0.38 | 0.624 |
| 9 | C | Y | I | R | L | P | Q | N | 0.31 | 0.624 |
| 10 | Y | Y | I | R | I | P | Q | N | 0.08 | 0.624 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR5B17.aApr07-unspliced | main_exon | 3UTR | chr11 | 58,358,125 | 58,358,128 | - |
| CDS | chr11 | 58,358,128 | 58,359,069 | - | ||