OR7A10 Olfactory Receptor
| Gene Symbol | OR7A101 (View this gene in GeneCards) |
| Family | 7 |
| Subfamily | A |
| Pseudogene | No |
| CORP pseudogene probability score | 0.04 (functional) |
| Aliases | OR19-18, CIT-HSP-146e8, OST027, HsOR19.3.3, ORL3773 |
| External Ids | HGNC: 8356 GeneBank: AF399542, BK004222, NM_001005190 ORDB: ORL3773 |
| Build #39 labels | OR7A10 |
| Chromosomal location | 19:14,840,951-14,841,877 (-) |
| Cluster | 19@15a |
| Synteny | CLIC#45 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR7A17 | 82.52% | 309 |
| OR7A2P | 80.58% | 309 |
| OR7A8P | 81.23% | 309 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR7A51 | 79% | 302 |
| Mouse | Or7a40 | 75% | 309 |
| Rat | Or7a41 | 77% | 303 |
| Cow | OR7A65 | 78% | 308 |
| Orang | OR7A10C | 86% | 309 |
| Orang | OR7A10D | 83% | 308 |
| Horse | OR7A96 | 80% | 305 |
| Chimp | OR7A2P | 82% | 305 |
| Chimp | OR7A8P | 81% | 309 |
| Chimp | OR7A5 | 81% | 301 |
Expression evidences
| Source | Accession |
|---|---|
| GNF Atlas2 | 217316_at |
Sequence information
| Nucleotide sequence |
ATGAAATCATGGAACAATACAATAATTTTAGAATTTCTTCTCCTGGGAATTTCAGAGGAA CCAGAATTGCAGGCCTTCCTCTTTGGGCTGTTCCTGTCCATGTACCTGGTCACTGTGCTC GGGAACCTGCTCATCATCCTGGCCACAATCTCAGACTCCCACCTCCACACCCCCATGTAC TTCTTCCTCTCCAACCTGTCCTTCGTAGACATCTGTTTTGTCTCTACCACTGTCCCGAAG ATGCTGGTGAACATCCAGACACACAACAAAGTCATCACCTATGCAGGCTGCATCACCCAG ATGTGCTTTTTCTTACTCTTTGTAGGATTGGATAACTTCCTTCTGACCGTGATGGCCTAT GACCGGTTTGTGGCCATCTGTCACCCTCTGCACTACATGGTCATTATGAACCCTCAACTC TGTGGACTGCTGGTTCTGGCATCCTGGATCATGAGTGTTCTGAATTCCATGTTACAAAGC TTAATGGTGTTGCCACTGCCCTTTTGTACACACATGGAAATCCCTCATTTTTTCTGTGAA ATTAATCAGGTGGTCCACCTTGCCTGTTCTGACACCTTTCTTAATGACATAGTGATGTAT TTTGCAGTAGCGCTGCTGGGCGGTGGTCCCCTCACTGGGATCCTGTACTCTTACTCTAAG ATAGTTTCCTCCATACGTGCAATCTCATCAGCTCAGGGGAAGTATAAGGCATTTTCCACC TGTGCATCTCACCTCTCAGTTGTCTCCTTATTTTATGGTACATGCTTAGGGGTGTACCTT AGTTCTGCTGCCACCCACAATTCACACACAGGTGCTGCAGCCTCAGTGATGTACACTGTG GTCACCCCCATGCTGAACCCCTTCATCTACAGTCTGAGGAATAAACACATAAAGGGTGCT ATGAAAACATTCTTCAGAGGAAAGCAA |
| Conceptual translation |
MKSWNNTIILEFLLLGISEEPELQAFLFGLFLSMYLVTVLGNLLIILATISDSHLHTPMY FFLSNLSFVDICFVSTTVPKMLVNIQTHNKVITYAGCITQMCFFLLFVGLDNFLLTVMAY DRFVAICHPLHYMVIMNPQLCGLLVLASWIMSVLNSMLQSLMVLPLPFCTHMEIPHFFCE INQVVHLACSDTFLNDIVMYFAVALLGGGPLTGILYSYSKIVSSIRAISSAQGKYKAFST CASHLSVVSLFYGTCLGVYLSSAATHNSHTGAAASVMYTVVTPMLNPFIYSLRNKHIKGA MKTFFRGKQ Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 19 | 100 | -100 | NS | G/C | Q/E | 1000GP (YRI, YRI) |
| 19 | 100 | -100 | SYN | A/G | N/N | 1000GP (YRI, YRI, YRI) |
| 19 | 14,841,077 | 14,841,077 | SYN | A/G | N/N | 1000GP (CEU, CHBJPT) |
| 19 | 14,841,086 | 14,841,086 | SYN | G/T | A/A | 1000GP (CEU, CHBJPT) |
| 19 | 14,841,426 | 14,841,426 | NS | A/G | M/T | 1000GP (CEU, CHBJPT) |
| 19 | 14,951,873 | 14,951,873 | NS | C/T | A/T | rs10221530 (DbSNP) |
| 19 | 14,951,889 | 14,951,889 | SYN | A/G | N/N | rs3752194 (DbSNP) |
| 19 | 14,951,898 | 14,951,898 | SYN | G/T | A/A | rs3752195 (DbSNP) |
| 19 | 14,952,017 | 14,952,017 | NS | A/T | L/I | rs11880955 (DbSNP) |
| 19 | 14,952,143 | 14,952,143 | NS | C/G | E/Q | rs9305052 (DbSNP) |
| 19 | 14,952,238 | 14,952,238 | NS | A/G | M/T | rs12972670 (DbSNP) |
| 19 | 14,952,560 | 14,952,560 | NS | G/T | L/I | rs12985894 (DbSNP) |
| 19 | 14,952,583 | 14,952,583 | NS | A/G | L/P | rs28540032 (DbSNP) |
Variations - CNVs
| Chr | Start | End | Type | Sources |
|---|---|---|---|---|
| CopyNumber | 183 (Hasin) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| Y290C | H266R | V247D | I225L | Y216F | Q183E | M151T | S67C | L36P | % Freq | CORP | |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Y | H | V | I | Y | Q | M | S | L | 81.95 | 0.078 |
| 2 | Y | H | V | L | Y | Q | T | S | L | 12.21 | 0.078 |
| 3 | Y | H | V | I | Y | E | M | S | L | 2.92 | 0.078 |
| 4 | Y | H | V | L | Y | Q | M | S | P | 1.77 | 0.078 |
| 5 | Y | R | V | I | Y | Q | M | S | L | 0.31 | 0.078 |
| 6 | Y | H | V | L | Y | Q | M | S | L | 0.23 | 0.078 |
| 7 | Y | H | V | I | Y | Q | M | S | P | 0.15 | 0.078 |
| 8 | C | R | V | I | Y | Q | M | S | L | 0.15 | 0.078 |
| 9 | Y | H | V | I | Y | E | M | C | L | 0.08 | 0.006 |
| 10 | Y | H | D | I | Y | Q | M | S | L | 0.08 | 0.098 |
| 11 | Y | H | V | I | F | Q | M | S | L | 0.08 | 0.078 |
| 12 | Y | H | V | L | Y | Q | T | S | P | 0.08 | 0.078 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR7A10.aApr07-unspliced | main_exon | 3UTR | chr19 | 14,840,948 | 14,840,951 | - |
| CDS | chr19 | 14,840,951 | 14,841,877 | - | ||