OR2B11 Olfactory Receptor
Gene Symbol | OR2B111 (View this gene in GeneCards) |
Family | 2 |
Subfamily | B |
Pseudogene | No |
CORP pseudogene probability score | 0.28 (functional) |
Aliases | HsOR1.5.1 |
External Ids | HGNC: 31249 GeneBank: NM_001004492 |
Build #39 labels | |
Chromosomal location | 1:247,451,032-247,451,982 (-) |
Cluster | 1@248 |
Synteny | CLIC#5 |
Remarks |
Most Similar ORs in Humans (Paralogs)
Symbol | Percent | Length |
---|---|---|
OR2B2 | 58.53% | 299 |
OR2B3 | 59.27% | 302 |
OR2B4P | 61.36% | 308 |
Most Similar ORs in other species (Orthologs)
Specie | Symbol | Percent | Length |
---|---|---|---|
Dog | OR2B2 | 63% | 301 |
Mouse | Or2b11 | 87% | 317 |
Rat | Or2b11 | 84% | 317 |
Cow | OR2B2 | 63% | 300 |
Orang | OR2B4P | 62% | 311 |
Horse | OR2B2 | 63% | 303 |
Chimp | OR2B3 | 59% | 303 |
Expression evidences
Source | Accession |
---|---|
ESTs | BF838729 |
mRNA | BC137205 |
GNF Atlas2 | gnf1h09716_at |
Sequence information
Nucleotide sequence |
ATGAAAAGTGACAACCATAGCTTCTTAGGGGACTCCCCTAAAGCCTTCATCCTTCTGGGT GTGTCTGACAGGCCGTGGCTGGAACTCCCTCTCTTTGTGGTCCTCCTGCTGTCCTATGTG CTGGCCATGTTGGGGAACGTCGCCATCATCCTGGCATCCCGGGTGGATCCTCAACTCCAC AGCCCCATGTACATCTTCCTCAGTCACCTGTCCTTCCTGGACCTCTGCTACACCACCACG ACAGTCCCTCAGATGCTGGTCAACATGGGCAGTTCCCAGAAGACCATCAGCTATGGAGGC TGCACTGTGCAATATGCAGTCTTCCACTGGCTGGGATGCACGGAGTGCATCGTCCTGGCC GCCATGGCCCTGGACCGCTACGTGGCCATCTGCAAGCCCCTGCACTATGCCGTTCTCATG CACCGTGCTCTCTGTCAGCAGCTCGTGGCTCTGGCCTGGCTCAGTGGCTTCGGCAACTCC TTCGTGCAGGTGGTCCTGACGGTGCAATTGCCATTCTGCGGGCGGCAGGTGCTGAACAAC TTTTTCTGTGAGGTGCCGGCCGTGATCAAGCTGTCGTGTGCTGACACCGCTGTGAATGAC ACCATACTGGCTGTGCTGGTGGCCTTCTTCGTGTTGGTGCCCCTGGCTCTCATCCTTCTC TCCTATGGCTTTATTGCCCGGGCAGTGCTCAGGATCCAGTCCTCCAAGGGACGACACAAG GCCTTTGGGACGTGTTCCTCCCACCTGATGATCGTCTCCCTCTTCTACCTACCTGCGATT TACATGTATCTGCAGCCCCCTTCCAGCTACTCCCAAGAGCAGGGCAAATTTATTTCTCTC TTCTATTCCATAATCACCCCCACTCTCAATCCCTTCACCTACACCCTGAGAAATAAAGAT ATGAAGGGGGCTCTGAGGAGACTTCTGGCCAGGATCTGGAGGCTCTGTGGA |
Conceptual translation |
MKSDNHSFLGDSPKAFILLGVSDRPWLELPLFVVLLLSYVLAMLGNVAIILASRVDPQLH SPMYIFLSHLSFLDLCYTTTTVPQMLVNMGSSQKTISYGGCTVQYAVFHWLGCTECIVLA AMALDRYVAICKPLHYAVLMHRALCQQLVALAWLSGFGNSFVQVVLTVQLPFCGRQVLNN FFCEVPAVIKLSCADTAVNDTILAVLVAFFVLVPLALILLSYGFIARAVLRIQSSKGRHK AFGTCSSHLMIVSLFYLPAIYMYLQPPSSYSQEQGKFISLFYSIITPTLNPFTYTLRNKD MKGALRRLLARIWRLCG Protein domains and features |
Variations - SNPs
Chr | Start | End | Type | Variation | AA Change | SNP IDs |
---|---|---|---|---|---|---|
1 | 100 | -100 | NS | T/C | D/G | 1000GP (YRI, YRI, YRI, YRI, YRI, YRI, YRI, YRI, YRI) |
1 | 100 | -100 | SYN | C/T | T/T | 1000GP (YRI, YRI, YRI, YRI) |
1 | 247,451,084 | 247,451,084 | NS | T/C | D/G | 1000GP (CEU) |
1 | 247,451,105 | 247,451,105 | NS | G/A | T/I | 1000GP (CEU) |
1 | 247,451,251 | 247,451,251 | SYN | C/T | T/T | 1000GP (CEU) |
1 | 247,451,315 | 247,451,315 | NS | C/T | G/D | 1000GP (CEU, CHBJPT) |
1 | 247,451,367 | 247,451,367 | NS | G/C | L/V | 1000GP (CHBJPT) |
1 | 247,451,369 | 247,451,369 | NS | A/C | V/G | 1000GP (CHBJPT) |
1 | 247,451,391 | 247,451,391 | NS | C/T | V/M | 1000GP (CEU, CHBJPT) |
1 | 247,451,448 | 247,451,448 | NS | T/C | N/D | 1000GP (CHBJPT) |
1 | 247,451,594 | 247,451,594 | NS | A/C | I/S | 1000GP (CEU, CHBJPT) |
1 | 247,451,950 | 247,451,950 | SYN | G/A | D/D | 1000GP (CEU, CHBJPT) |
1 | 247,614,386 | 247,614,386 | NS | C/T | G/D | rs12070953 (DbSNP) |
1 | 247,614,407 | 247,614,407 | NS | A/G | I/T | rs12065526 (DbSNP) |
1 | 247,614,553 | 247,614,553 | SYN | C/T | T/T | rs12086048 (DbSNP) |
1 | 247,614,617 | 247,614,617 | NS | C/T | G/D | rs4925663 (DbSNP) |
1 | 247,614,657 | 247,614,657 | NS | A/G | F/L | rs73140586 (DbSNP) |
1 | 247,614,693 | 247,614,693 | NS | C/T | V/M | rs6695302 (DbSNP) |
1 | 247,614,763 | 247,614,763 | SYN | C/T | G/G | rs58058243 (DbSNP) |
1 | 247,614,784 | 247,614,784 | SYN | C/G | T/T | rs74154654 (DbSNP) |
1 | 247,614,896 | 247,614,896 | NS | A/C | I/S | rs11583410 (DbSNP) |
1 | 247,614,925 | 247,614,925 | SYN | A/G | A/A | rs73140588 (DbSNP) |
1 | 247,615,154 | 247,615,153 | Ins(1) | -/C | rs35822304 (DbSNP) | |
1 | 247,615,252 | 247,615,252 | SYN | A/G | D/D | rs12028142 (DbSNP) |
1 | 247,615,263 | 247,615,263 | Del(1) | -/A | rs35305980 (DbSNP) |
Variations - CNVs
Chr | Start | End | Type | Sources |
---|---|---|---|---|
1 | 247,074,430 | 248,328,835 | CopyNumber | Variation_6816 (DGV) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
D300G | T293I | N290H | R231M | R227W | G223D | F210L | D200E | V198M | N179D | I130S | N46S | S12Y | % Freq | CORP | |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | D | T | N | R | R | D | F | D | M | N | I | N | S | 32.26 | 0.209 |
2 | D | T | N | R | R | G | F | D | M | N | S | N | S | 29.26 | 0.720 |
3 | D | T | N | R | R | G | F | D | M | N | I | N | S | 13.90 | 0.209 |
4 | G | I | N | R | R | G | F | D | M | N | I | N | S | 7.60 | 0.209 |
5 | D | T | N | R | R | D | F | D | M | N | S | N | S | 4.99 | 0.720 |
6 | D | T | N | R | R | G | L | D | V | N | I | N | S | 4.15 | 0.209 |
7 | G | I | N | R | R | G | L | D | V | N | I | N | S | 1.46 | 0.209 |
8 | G | I | N | R | W | G | L | D | V | N | I | N | S | 0.77 | 0.209 |
9 | G | I | N | R | R | G | F | D | V | N | I | N | S | 0.61 | 0.209 |
10 | D | T | N | R | R | G | L | D | V | N | S | N | S | 0.61 | 0.720 |
11 | D | T | N | R | R | D | F | D | V | N | I | N | S | 0.61 | 0.209 |
12 | D | T | N | R | R | G | F | D | V | N | I | N | S | 0.54 | 0.209 |
13 | D | T | N | R | R | G | F | D | M | N | S | S | S | 0.38 | 1.000 |
14 | D | T | N | R | R | D | F | D | M | D | I | N | S | 0.38 | 0.209 |
15 | G | I | N | R | R | G | L | E | V | N | I | N | S | 0.31 | 0.209 |
16 | D | I | N | R | R | G | F | D | M | N | I | N | S | 0.23 | 0.209 |
17 | G | I | N | R | R | G | F | D | M | N | S | N | S | 0.23 | 0.720 |
18 | D | T | N | R | R | G | F | D | M | N | S | N | Y | 0.15 | 0.720 |
19 | D | T | H | R | R | D | F | D | M | N | I | N | S | 0.15 | 0.119 |
20 | D | T | N | R | W | G | F | D | M | N | S | N | S | 0.15 | 0.720 |
21 | D | T | N | R | R | G | F | D | V | N | S | N | S | 0.15 | 0.720 |
22 | D | T | N | R | R | D | F | D | V | N | S | N | S | 0.15 | 0.720 |
23 | D | T | N | R | R | G | F | D | M | N | I | S | S | 0.15 | 1.000 |
24 | D | T | N | R | R | G | L | D | V | N | I | S | S | 0.15 | 1.000 |
25 | D | T | N | R | R | D | F | D | M | D | S | N | S | 0.08 | 0.720 |
26 | D | I | N | R | R | D | F | D | M | N | I | N | S | 0.08 | 0.209 |
27 | D | T | N | R | R | G | F | D | V | N | S | S | S | 0.08 | 1.000 |
28 | D | I | N | R | R | G | F | D | M | N | S | N | S | 0.08 | 0.720 |
29 | D | T | N | R | R | G | L | D | M | N | I | N | S | 0.08 | 0.209 |
30 | D | T | N | R | R | G | F | D | M | N | I | N | Y | 0.08 | 0.209 |
31 | G | I | N | R | R | D | F | D | M | N | I | N | S | 0.08 | 0.209 |
32 | D | T | N | M | R | G | F | D | M | N | I | N | S | 0.08 | 0.209 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
Accession | Type | Chr | Start | End | Strand | |
---|---|---|---|---|---|---|
OR2B11.aApr07-unspliced | main_exon | 3UTR | chr1 | 247,451,029 | 247,451,032 | - |
CDS | chr1 | 247,451,032 | 247,451,982 | - |