OR2Y1 Olfactory Receptor
Gene Symbol | OR2Y11 (View this gene in GeneCards) |
Family | 2 |
Subfamily | Y |
Pseudogene | No |
CORP pseudogene probability score | 0.25 (functional) |
Aliases | OR5-2, HsOR5.4.2, ORL3131 |
External Ids | HGNC: 14837 GeneBank: AB065676, AF399629, BK004351, NM_001001657 ORDB: ORL3131 |
Build #39 labels | OR2Y1 |
Chromosomal location | 5:180,739,126-180,740,058 (-) |
Cluster | 5@180 |
Synteny | CLIC#11 |
Remarks |
Most Similar ORs in Humans (Paralogs)
Symbol | Percent | Length |
---|---|---|
OR2B7P | 60.59% | 307 |
OR2B8P | 63.34% | 311 |
OR2W6P | 59.54% | 304 |
Most Similar ORs in other species (Orthologs)
Specie | Symbol | Percent | Length |
---|---|---|---|
Dog | OR2B8 | 63% | 307 |
Mouse | Or2y1 | 83% | 309 |
Mouse | Or2y1c | 83% | 309 |
Mouse | Or2y1e | 81% | 310 |
Mouse | Or2y1d | 80% | 309 |
Rat | Or2y1g | 82% | 311 |
Rat | Or2y1c | 83% | 309 |
Rat | Or2y1h | 82% | 307 |
Rat | Or2y1e | 81% | 310 |
Cow | OR2B8H | 63% | 312 |
Orang | OR2Y1P | 95% | 309 |
Horse | OR2B8B | 65% | 307 |
Chimp | OR2G3 | 61% | 305 |
Expression evidences
Source | Accession |
---|---|
mRNA | BC140756 |
Sequence information
Nucleotide sequence |
ATGGGAAGTTTCAACACCAGTTTTGAAGATGGCTTCATTTTGGTGGGATTCTCAGATTGG CCGCAACTGGAGCCCATCCTGTTTGTCTTTATTTTTATTTTCTACTCCCTAACTCTCTTT GGCAACACCATCATCATCGCTCTCTCCTGGCTAGACCTTCGGCTGCACACACCTATGTAC TTCTTTCTCTCTCATCTGTCCCTCCTGGACCTCTGCTTCACCACCAGCACCGTGCCCCAG CTCCTGATCAACCTTTGCGGGGTGGACCGCACCATCACCCGTGGAGGGTGTGTGGCTCAG CTCTTCATCTACCTAGCCCTGGGCTCCACAGAGTGTGTGCTCCTGGTGGTGATGGCCTTT GACCGCTATGCTGCTGTCTGTCGTCCACTCCACTACATGGCCATCATGCACCCCCATCTC TGCCAGACCCTGGCTATCGCCTCCTGGGGTGCGGGTTTCGTGAACTCTCTGATCCAGACA GGTCTCGCAATGGCCATGCCTCTCTGTGGCCATCGACTGAATCACTTCTTCTGTGAGATG CCTGTATTTCTGAAGTTGGCTTGTGCGGACACAGAAGGAACAGAGGCCAAGATGTTTGTG GCCCGAGTCATAGTCGTGGCTGTTCCTGCAGCACTTATTCTAGGCTCCTATGTGCACATT GCTCATGCAGTGCTGAGGGTGAAGTCAACGGCTGGGCGCAGAAAGGCTTTTGGGACTTGT GGGTCCCACCTCCTAGTAGTTTTCCTTTTTTATGGCTCAGCCATCTACACATATCTCCAA TCCATCCACAATTATTCTGAGCGTGAGGGAAAATTTGTTGCCCTTTTTTATACTATAATT ACCCCCATTCTCAATCCTCTCATTTATACACTAAGAAACAAGGACGTGAAGGGGGCTCTG TGGAAAGTACTATGGAGGGGCAGGGACTCAGGG |
Conceptual translation |
MGSFNTSFEDGFILVGFSDWPQLEPILFVFIFIFYSLTLFGNTIIIALSWLDLRLHTPMY FFLSHLSLLDLCFTTSTVPQLLINLCGVDRTITRGGCVAQLFIYLALGSTECVLLVVMAF DRYAAVCRPLHYMAIMHPHLCQTLAIASWGAGFVNSLIQTGLAMAMPLCGHRLNHFFCEM PVFLKLACADTEGTEAKMFVARVIVVAVPAALILGSYVHIAHAVLRVKSTAGRRKAFGTC GSHLLVVFLFYGSAIYTYLQSIHNYSEREGKFVALFYTIITPILNPLIYTLRNKDVKGAL WKVLWRGRDSG Protein domains and features |
Variations - SNPs
Chr | Start | End | Type | Variation | AA Change | SNP IDs |
---|---|---|---|---|---|---|
5 | 180,166,677 | 180,166,677 | NS | A/G | C/R | rs11960429 (DbSNP) |
5 | 180,166,877 | 180,166,877 | NS | A/T | F/Y | rs73815111 (DbSNP) |
5 | 180,166,461 | 180,166,461 | NS | C/G | V/L | rs10464105 (DbSNP) |
5 | 180,166,599 | 180,166,599 | NS | C/T | V/M | rs11954074 (DbSNP) |
5 | 180,166,362 | 180,166,362 | NS | G/A | R/C | rs61736842 (DbSNP) |
5 | 180,166,866 | 180,166,866 | NS | G/A | H/Y | rs61737927 (DbSNP) |
5 | 180,166,361 | 180,166,361 | NS | T/C | H/R | rs61736845 (DbSNP) |
5 | 180,166,256 | 180,166,256 | NS | T/C | H/R | rs61735555 (DbSNP) |
5 | 180,166,164 | 180,166,164 | NS | T/C | T/A | rs61737057 (DbSNP) |
5 | 180,166,141 | 180,166,141 | SYN | C/T | R/R | rs9329115 (DbSNP) |
5 | 180,166,834 | 180,166,834 | SYN | T/G | T/T | rs61737915 (DbSNP) |
5 | 180,739,461 | 180,739,461 | NS | C/G | V/L | 1000GP (CEU) |
5 | 180,739,599 | 180,739,599 | NS | C/T | V/M | 1000GP (CEU) |
5 | 180,739,141 | 180,739,141 | SYN | C/T | R/R | 1000GP (CHBJPT) |
5 | 100 | -100 | SYN | C/T | R/R | 1000GP (YRI) |
5 | 100 | -100 | NS | C/T | R/H | 1000GP (YRI, YRI, YRI, YRI, YRI, YRI, YRI) |
Variations - CNVs
Chr | Start | End | Type | Sources |
---|---|---|---|---|
5 | 180,079,970 | 180,245,224 | CopyNumber | Variation_2612 (DGV) |
5 | 180,087,198 | 180,281,476 | CopyNumber | Variation_3592 (DGV) |
5 | 180,136,233 | 180,226,673 | CopyNumber | Variation_34493 (DGV) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
G307C | R268H | R233H | R233C | V154M | R128C | A106V | H65Y | F61Y | R54W | % Freq | CORP | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | G | R | R | R | V | R | A | H | F | R | 92.55 | 0.454 |
2 | G | R | H | R | V | R | A | H | F | R | 1.84 | 0.454 |
3 | G | R | R | R | M | C | A | H | F | R | 1.31 | 0.454 |
4 | G | H | R | C | V | R | A | Y | Y | R | 1.08 | 0.407 |
5 | G | H | R | C | V | R | A | H | F | R | 0.61 | 0.407 |
6 | G | R | R | R | V | R | A | Y | Y | R | 0.61 | 0.454 |
7 | G | R | R | R | M | R | A | H | F | R | 0.31 | 0.454 |
8 | G | H | R | R | V | R | A | H | F | R | 0.31 | 0.454 |
9 | G | R | R | R | V | R | V | H | F | R | 0.31 | 0.454 |
10 | G | R | R | R | V | R | A | Y | F | W | 0.23 | 0.454 |
11 | C | R | R | R | V | R | A | H | F | R | 0.23 | 0.454 |
12 | G | R | R | C | V | R | A | H | F | R | 0.23 | 0.407 |
13 | G | R | H | R | V | R | A | Y | F | R | 0.23 | 0.454 |
14 | G | R | R | R | V | C | A | H | F | R | 0.08 | 0.454 |
15 | G | R | R | R | V | R | A | Y | F | R | 0.08 | 0.454 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
Accession | Type | Chr | Start | End | Strand | |
---|---|---|---|---|---|---|
OR2Y1.aApr07-unspliced | main_exon | 3UTR | chr5 | 180,739,123 | 180,739,126 | - |
CDS | chr5 | 180,739,126 | 180,740,058 | - |